Prof Amitabha Bandyopadhyay

Amitabha is an associate professor in the department of Biological Sciences and Bioengineering at Indian Institute of Technology Kanpur. He conducted his doctoral research in the laboratory of Prof. Umadas Maitra at Albert Einstein College of Medicine in New York and postdoctoral research in the laboratory of Prof. Clifford Tabin at Harvard Medical School.

Amitabha studies patterning and differentiation of skeletal elements using chick and mouse as model systems. He is particularly interested in learning about the molecular mechanism of joint cartilage differentiation and maintenance. Amitabha’s group proposed a model for simultaneous differentiation of joint and bone forming cartilage from a common pool of progenitor cells. His group also elucidated the molecular basis of mechano-sensitive maintenance of joint cartilage in developing embryos. He uses this line of investigation to understand the pathology of osteoarthritis. According to his working hypothesis osteoarthritis results from trans-differentiation of joint cartilage to bone forming cartilage.